The Rosalyn Yalow Charter School fosters a collaborative learning environment, using arts, music, and disciplined activities such as chess and fencing to engage the children and their families in the education process. The school will have a longer school day, 8 a.m.-5 p.m., and integrate academic teaching with arts, music, chess, and fencing throughout the day (no after-school programs). Yalow Charter School will be data-driven, using the NWEA and STEP assessment programs to guide teachers, administrators, and Board members in making professional development decisions.  In addition to two teachers in each classroom, there will be a Response to Intervention team, staffed with special education and English language learning teachers reporting to the director of assessment.

On June 24, 2014, the NYS Board of Regents voted to approve the charter opening in September 2015 in District 10, Bronx, NY. The Rosalyn Yalow Charter School is a tuition free public charter school, open to all New York State residents.